For decades,
discovering novel antibiotics meant digging through the same patch of dirt.
Biologists spent countless hours screening soil-dwelling microbes for
properties known to kill harmful bacteria. But as superbugs resistant to
existing antibiotics have spread widely, breakthroughs were becoming as rare as
new places to dig.
Now,
artificial intelligence is giving scientists a reason to dramatically expand
their search into databases of molecules that look nothing like existing
antibiotics.
A study published Thursday in the journal
Cell describes how researchers at the Massachusetts Institute of Technology
used machine learning to identify a molecule that appears capable of countering
some of the world’s most formidable pathogens.
When
tested in mice, the molecule, dubbed halicin, effectively treated the
gastrointestinal bug Clostridium difficile (C. diff), a common killer of
hospitalized patients, and another type of drug-resistant bacteria that often
causes infections in the blood, urinary tract, and lungs.
The
most surprising feature of the molecule? It is structurally distinct from
existing antibiotics, the researchers said. It was found in a drug-repurposing
database where it was initially identified as a possible treatment for
diabetes, a feat that showcases the power of machine learning to support
discovery efforts.
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New cash machines: withdraw money with veins in your finger Cash machine technology that reads the pattern of finger veins is already available in Japan and Poland By Telegraph Reporters 6:59PM BST 15 May 2014 Cash machines could soon be installed with devices that identify customers by reading the veins in their fingers. The technology is already being rolled out in Poland, where 1,730 cash machines will this year be installed with readers, negating the need for a debit card and Pin. Developed by Hitachi, the Japanese electronics firm, the machines read the patterns of the veins just below the surface of the skin on your finger using infra-red sensors. The light is partially absorbed by haemoglobin in the veins to capture a unique finger vein pattern profile, which is matched to a profile. The technology is used by Japanese banks and also in Turkey, offering “groundbreaking levels of accuracy and speed of authentication”, Hitachi said, which in t...
Scientists discover ‘magical’ material that’s stronger than steel and lighter than aluminum — and its potential is dizzying Story by Rick Kazmer • September 21, 2023 Galvorn is stronger than steel, lighter than aluminum, and has the conductivity of copper, according to an article on LinkedIn. While the jury is still out on whether it’s faster than a speeding bullet, experts at Houston-based DexMat suggest their product can revolutionize the green tech landscape. Galvorn can be an alternative to rare and expensive copper — a crucial metal in electronics, according to a report from GreenBiz. What’s more, the inventors plan to displace dirty materials, contribute to cleaner air, and advance green tech as their “magical” material is rolled out. Galvorn is the result of a more than $20 million investment from two U.S. Air Force research agencies, the Department of Energy, and NASA, among other tech heavy hitters, GreenBiz reports. “DexMat’s potential climate impact gets us dizzy,” ...
BMW traps alleged thief by remotely locking him in car Stealer's Wheel? Seattle police department quotes "Watchmen" movie in a recap of the recent arrest. Tech Culture by Gael Fashingbauer Cooper December 4, 2016 5:00 PM PST It's maybe the most satisfying arrest we can imagine. Seattle police caught an alleged car thief by enlisting the help of car maker BMW to both track and then remotely lock the luckless criminal in the very car he was trying to steal. Jonah Spangenthal-Lee, deputy director of communications for the Seattle Police Department, posted a witty summary of the event on the SPD's blog on Wednesday. Turns out if you're inside a stolen car, it's perhaps not the best time to take a nap. "A car thief awoke from a sound slumber Sunday morning (Nov. 27) to find he had been remotely locked inside a stolen BMW, just as Seattle police officers were bearing down on him," Spangenthal-Lee wrote. The suspect found a ke...
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